Essential role of membrane cholesterol in accelerated bcr internalization and uncoupling from nf κb in b cell clonal anergy.
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Na k atpase was originally discovered as an ion pump that is essential for cell vitality and provides a means for epithelium to secrete and or absorb solutes and nutrients 1 2 recent studies have revealed that in addition to pumping ions across the cell membrane na k atpase specifically the α1 isoform conducts many nonpumping functions including scaffolding and signal.
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Primary mouse b cells repair pm wounds in a ca 2 dependent manner.
Using invoke as a task runner in python last updated on january 29 2019.
In a similar manner the syk inhibitor sykii abrogated the phosphorylation of slp76 and even depleted the basal level.
Invoke is a python 2 7 and 3 4 task execution tool library drawing inspiration from various sources to arrive at a powerful clean feature set.
To determine whether b cells are capable of repairing pm wounds primary b cells freshly isolated from mouse spleens were incubated with increasing concentrations of slo 0 to 400 ng ml with or without ca 2 in the culture medium.
Blery m tze l miosge la jun je goodnow cc.
Pp2 and sykii also partially inhibited the phosphorylation of slp76 s376 residue figure 3b.
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Slo is a bacterial toxin that binds to cholesterol in membranes and oligomerizes into pores.